"May the gods have mercy. For I have none."

A titanic detonation erupts from the caster, sending a mushroom plume into the sky above. The most powerful destructive spell a mage can cast, it leaves nothing left but a horrid scar upon the earth where it was cast. At the cost of this spell is the very life of the caster, and a very rare and strange material called Uranium. The spell has been used few times throughout history, if ever, and always at a moment of absolute carnage. A wizard turns back, teary eyed to his friends as they teleport away, the Tarrasque a single turn away from being let loose free unto the world, before casting this spell. In a moment, the Tarrasque is gone, and his party look on as the sky turns a hue of red, the distant horizon dawning what looks like a second sun.

All creatures within 300 feet of the caster, including the caster, die instantly.

From 300 to 1 mile from the caster, a creature takes 90 (10d10+40) Fire + 90 (10d10+40) Radiant damage, alongside 35 (10d6) Thunder damage.

From 1 mile to 5 miles from the caster, a creature instead takes 18 (5d6) Fire + 18 (5d6) Radiant damage. 

From 5 miles to 10 miles from the caster, a creature instead takes 3 (1d6) Fire + 3 (1d6) Radiant damage.

Within 300 feet of the detonation, a sickly radioactive hue remains for 100 (4d4*10) years, causing 10 Radiant damage per turn to anything within the radius.

Within 1 mile of the detonation, a passive radioactive hue remains for 50 (2d4*10) years, causing 1 Radiant damage per turn to anything within the radius.

Within 10 miles of the detonation, no life naturally grows, crops wither and die if planted, children born within the area are deformed, and remaining within the radius for over a year will cause a creature to take a permanent -1 to CON every year until death.