Drain humors

With a touch, the caster drains a humor from the target, resulting in disadvantage for saves and skills checks for the ability score related to that humor. The spell is resisted by the ability score that opposes that humor.  The target can re roll a save at the end of their subsequent turns to overcome the spell.

blood - disadvantage to dexterity saves and skill checks, resisted by a Charisma save

yellow bile - disadvantage to strength saves and skill checks, resisted by  Constitution save

black bile - disadvantage to charisma saves and skill checks, resisted by a Dexterity save  

phlegm - disadvantage to constitution saves and skill checks, resisted by a Strength save