Annihilation bolt

A bright white beam shoots from your pointing finger to a point you choose within range and then booms with a deafening boom and a blinding flash into an explosion of pure destruction. One creature or object in range must make a Dexterity saving throw. A target takes 20d6 fire damage on a failed save, or half as much damage on a successful one. All creatures in 20 feet of the target must make a constitution saving throw or be permanently be blinded and deafened which can be healed with greater restoration or wish. Creatures dropped to 0 hit points are erased from existence and can only be resurrected with true restoration or wish

Inanimate objects are erased from existence with no save against the spell