You get frustrated at the intellegence of people and cast a spell that does more damage the higher the intellect. Each creature with an intellegence score 10 or higher must make a DC 25 Dexterity saving throw*(You can cause members of your party to automatically succeed.) On a fail, the creature takes 10 x its intellegence score Meme damage. 

*Legendary smart monsters thought they could get out of it with Legendary Resistance!! HAHAHAHAha well legendary resistance does not apply with this spell.