Muff

Within range, point at a weapon held by a creature in its hands. The targeted weapon instantaneously starts to wriggle and squirm in the grasp of its wielder, requiring a successful Dexterity saving throw to maintain a hold on the weapon. On a failed save, the weapon squirts out of its wielder's grasp, landing harmlessly in an unoccupied square 10 feet away (in a direction of the Dungeon Master's choosing).

If the weapon is wielded with two hands, the saving throw is made with advantage.