Crimson Anathema

You perform a horrific ritual that inflicts an ancient, reality-warping Blood Curse upon an entire region. This dreadful magic permeates the very soil, air, and water of an area up to 5 miles in radius centered on a point you choose within range, binding all living beings to a shared fate through their blood.

When the ritual is complete, every living creature with blood in the affected area must make a Constitution saving throw. On a failed save, the creature is afflicted with a Blood Curse of your design, which manifests immediately and becomes part of their bloodline, potentially passing to their descendants. Even creatures that succeed remain marked by the curse, becoming carriers who can spread it beyond the initial area.

Additionaly, you may state a condition under which the curse will be perished. The curse you create must follow these guidelines:

     It must involve blood or vital essence in some way

     It cannot immediately kill (though it may cause suffering or gradual decline)

     It must have at least one conditional trigger or limitation

     It must manifest visible signs (pallid skin, blood-red eyes, weeping wounds, etc.)

Sample curse effects include:

     All healing magic only functions at half effectiveness

     Blood slowly turns black, causing exhaustion levels that cannot be removed by normal rest

     Each full moon, afflicted creatures bleed from their eyes and are blinded for 24 hours

     Children born to afflicted parents have a 50% chance of manifesting supernatural abilities tied to blood

The curse becomes bound to the land itself, gradually transforming the environment to reflect its nature. Plants may weep crimson sap, water sources might turn blood-red during certain lunar phases, or animals could develop disturbing mutations.

This curse cannot be removed by anything less than a wish spell, divine intervention or fulfilling the conditions of removing specified by caster. Even these powerful forces can only cleanse a portion of the region at a time, requiring multiple applications to fully break the curse.

Blood Sacrifice. This spell exacts a terrible toll on the caster. When casting this spell, you take 10d10 necrotic damage that cannot be reduced or prevented in any way. This damage reduces your hit point maximum by the same amount, and this reduction cannot be restored by any means short of a wish spell or divine intervention. Additionally, you permanently lose 3 points from your Constitution score, and you yourself become afflicted with a milder version of the curse you create, forever marking you as its originator.

     If this spell reduces your hit point maximum to 0, you die and your body disintegrates into a pool of blood that seeps into the earth, becoming the epicenter of the cursed region