The Dr. Manhattan Special

This spell can only be casted on a creature that is sentient and capable of carrying a conversation with the PC. (Regardless of language barriers.)

On cast, this exchange must take place or the spell will not take effect:

Player: “It’s so sad that Steve Jobs died of Ligma.”

DM (as spell target): “Who the hell is Steve Jobs?”

Player: “Ligma Balls.”

On hit, the target will immediately take 200d6 psychic damage (time to get out the dice bucket), which will completely ignore resistance.