Bone Desecration

You force a creature to make a Charisma saving throw, which is modified based on the type of bone targeted in the creature, or have one of their bones teleported out of their body. The removed bone teleports and leaves the point of removal unmarred, and appears in your free hand. On a successful save, the creature isn’t affected, and you can’t use this spell against it again for 24 hours. The target automatically succeeds the save if they do not possess the targeted bone.

If the spell ends before 1 minute has passed, the bone reappears back in the creature's body. Any changes or alterations to the bone remain, regardless of if its current state no longer fits or functions properly. Otherwise, the bone doesn't return, and the effects created by its removal remain permanent. Once the effect is permanent, restoration spells like Regenerate can restore missing bones. Spells like Remove Curse or Greater Restoration do not, as the effect itself stems from the bone being missing, not the original spell itself.

Finger - The creature has disadvantage on Sleight of Hand checks.

Rib - The creature's hit point maximum is reduced by a number equal to the spell slot used to cast the spell times 3.

Arm - The creature gains a +5 to the saving throw. They cannot wield weapons or shields in that hand and drops whatever it is holding.

Leg - The creature gains +5 to the saving throw. Their speed is reduced by 10 feet and have disadvantage on saving throws against being knocked prone.

Spine - The target gains +8 to the saving throw, but becomes paralyzed on a failed save. They can still speak, however.

Skull - The target gains +12 to the saving throw, but becomes incapacitated and unconscious on a failed save, and dies if their skull is not returned after 1 minute if they are left undisturbed.