Desperation

Choose one creature that you can see within range. The target must succeed on a Constitution Saving Throw or be under the spell's effect for the duration. An affected creature has a -5 to all ability checks until it is able to "complete a task"* or 10 days have passed.

A Remove Curse, Greater Restoration, or Wish spell end the effect.

* please see full spell description in avrae - ask for assistance, if needed.