Curse

(ETERNAMANCY) You can cause a soul to be eternally cursed with some kind of negative magical effect. This can be any negative effect you want, as long as the DM allows it. Alternatively, you can eternally curse a family line. For example, you could curse a human with children and grandchildren. You could choose to also curse that human’s family line as well, making their children and grandchildren be cursed with the same effect, along with any children that came afterward. This curse can only be dispelled by a wish spell.