Mutagenists are alchemists who specialize in creating transformative elixirs called mutagens, which grant powerful boons and sometimes perilous drawbacks.

Through the study of biology, chemistry, and a bit of arcane lore, they enhance their own physical and mental capabilities temporarily, making themselves formidable in combat and versatile in many situations. They are also highly experimental in nature, sometimes creating custom mutagens tailored to their specific needs or the needs of their allies. In discussion with your DM, you can craft custom mutagens beyond those in the provided tables.

Tool Proficiency

When you adopt this specialization at 3rd level, you gain proficiency with alchemist's supplies. If you already have this proficiency, you gain proficiency with one other type of artisan's tools of your choice.

Mutagen Formula

Starting at 3rd level, you learn to create powerful mutagens that enhance your abilities at the cost of certain drawbacks. When you finish a long rest, you can use your alchemist's supplies to create a number of mutagens equal to your Intelligence modifier (minimum of one). These mutagens last until they are consumed or until the end of your next long rest.

As a bonus action, you can drink a mutagen or administer it to a willing creature within 5 feet of you. The effects of the mutagen last for 1 hour or until you or the recipient use a bonus action to end it. A creature can only benefit from one mutagen at a time.

At 3rd level, you learn three mutagens from the Mutagen Table. You learn one additional mutagen at 5th, 9th, and 15th levels. Each time you gain a level in this class, you can replace one mutagen you know with a different one from the table.

 

 

Mutagen Table

 

Mutagen	Effect	Drawback
Strength Mutagen	Gain a +3 bonus to Strength checks and saving throws.	Disadvantage on Dexterity checks and saving throws.
Agility Mutagen	Gain a +3 bonus to Dexterity checks and saving throws.	Disadvantage on Strength checks and saving throws.
Resilience Mutagen	Gain a +1 bonus to AC and saving throws.	Disadvantage on Dexterity saving throws.
Celerity Mutagen	Movement speed increases by 10 feet, advantage on initiative rolls.	Disadvantage on Wisdom checks and saving throws.
Clarity Mutagen	Gain advantage on Intelligence checks and saving throws.	Disadvantage on Charisma checks and saving throws.
Eagle Eye Mutagen	Gain advantage on Perception checks and darkvision for 60 feet.	Disadvantage on attack rolls against targets within 10 feet.
Iron Skin Mutagen	Gain resistance to non-magical bludgeoning, piercing, slashing damage.	Disadvantage on Dexterity checks and saving throws.
Spider Climb Mutagen	Gain a climbing speed equal to your walking speed.	Disadvantage on Charisma checks and saving throws.
Fireblood Mutagen	Deal fire damage equal to proficiency bonus when taking damage.	Disadvantage on Constitution checks and saving throws.
Gills Mutagen	Gain underwater breathing and a swimming speed equal to walking speed.	Disadvantage on Strength checks and saving throws.
Stone Skin Mutagen	Gain a +2 bonus to AC.	Movement speed reduced by 10 feet.
Bull’s Strength Mutagen	Gain advantage on Strength (Athletics) checks, double carrying capacity.	Disadvantage on Dexterity (Acrobatics) checks.
Nimble Mutagen	Gain advantage on Dexterity (Acrobatics) checks.	Disadvantage on Strength (Athletics) checks.
Frostblood Mutagen	Gain resistance to cold damage.	Disadvantage on Dexterity checks and saving throws.

Mutagenist Spells

These spells are always prepared.

Artificer Level	Spell
3rd	Enhance Ability, Alter Self
5th	Haste, Protection from Energy
9th	Gaseous Form, Water Breathing
13th	Stoneskin, Freedom of Movement
17th	Greater Restoration, Contagion

Advanced Mutagen

At 5th level, you learn to brew more potent mutagens. You can now choose from the advanced mutagens as well.

Advanced Mutagen Table

 

Mutagen	Effect	Drawback
Greater Strength Mutagen	Gain a +4 bonus to Strength checks and saving throws, double carrying capacity.	Disadvantage on Dexterity checks and saving throws, and movement speed reduced by 10 feet.
Greater Agility Mutagen	Gain a +4 bonus to Dexterity checks and saving throws, Dash action as bonus action.	Disadvantage on Strength checks and saving throws, -1 penalty to AC.
Greater Resilience Mutagen	Gain resistance to bludgeoning, piercing, and slashing damage.	Disadvantage on Dexterity saving throws, movement speed reduced by 10 feet.
Greater Celerity Mutagen	Movement speed increases by 20 feet, advantage on attack rolls during first turn in combat.	Disadvantage on Wisdom checks and saving throws, AC decreases by 1.
Greater Clarity Mutagen	Gain advantage on Intelligence and Wisdom checks and saving throws.	Disadvantage on Charisma checks and saving throws, -2 penalty to attack rolls.
Keen Senses Mutagen	Gain advantage on all Wisdom (Perception) checks, darkvision up to 120 feet.	Disadvantage on all Intelligence checks.
Serpent's Blood Mutagen	Gain advantage on saving throws against poison, resistance to poison damage.	Disadvantage on Constitution checks and saving throws.
Lightning Reflexes Mutagen	Gain a +2 bonus to Dexterity saving throws.	Disadvantage on Strength and Constitution checks.
Mind Focus Mutagen	Gain advantage on Intelligence saving throws and checks.	Disadvantage on Strength and Dexterity checks.

Experimental Mutagen

At 9th level, your alchemical research has allowed you to create a series of highly unpredictable and volatile mutagens. These Experimental Mutagens have powerful but unstable effects, making each use a gamble.

When you complete a long rest, you can prepare one Experimental Mutagen. When you or another creature consumes this mutagen, roll a d100 and consult the Experimental Mutagen Table to determine the effect. The mutagen's effect lasts for 10 minute unless otherwise stated. The side effects and drawbacks of these mutagens can be as severe as the benefits, so use them wisely.

You can create one Experimental Mutagen per long rest(In addition to the normal mutagens you can make from Mutagen Formula), unlike normal Mutagens, this form of Mutagen doesn't have an expiry period. However you can only have 3 Experimental Mutagens at any one given time.

If a creature consumes an additional Experimental Mutagen while already under the effects of one, the new mutagen immediately takes effect, and the previous one ends.

Experimental Mutagen Table

d100	Mutagen	Effect	Drawback

1-5

Shifting Density Mutagen

You gain resistance to all bludgeoning, piercing, and slashing damage.

You have disadvantage on all Dexterity saving throws and your movement speed is halved.

6-10

Phantom Mutagen

Gain the ability to pass through solid objects (up to 5 feet thick).

You take 1d6 force damage each time you pass through an object and have disadvantage on Strength saves.

11-15

Volcanic Skin Mutagen

When struck by a melee attack, you release a wave of fire (10-ft radius) dealing 2d6 fire damage.

You gain vulnerability to cold damage and take 1d6 fire damage at the start of your turn.

16-20

Feral Mind Mutagen

You gain advantage on melee attack rolls and deal an extra 1d8 damage.

You must use your action each turn to attack the nearest creature, friend or foe.

21-25

Spectral Vision Mutagen

Gain true sight up to 30 feet and advantage on all Perception checks.

You have disadvantage on all attack rolls against creatures within 10 feet of you.

26-30

Wraithwalk Mutagen

Gain the ability to teleport up to 30 feet as a bonus action.

After teleporting, you gain one level of exhaustion.

31-35

Monstrous Strength Mutagen

Your Strength score becomes 22.

You have disadvantage on Intelligence, Wisdom, and Charisma checks and saves while this is active.

36-40

Gorgon’s Gaze Mutagen

Once per short rest, as an action, you can force a creature to make a Constitution saving throw (DC 15) or be petrified for 1 minute.

You take 1d6 psychic damage whenever you deal damage to a creature.

41-45

Void Veins Mutagen

You can cast blink on yourself without expending a spell slot.

You lose concentration on any other spells while blink is active and take 1d4 psychic damage per turn.

46-50

Spider’s Grace Mutagen

Gain a climbing speed equal to your walking speed and can move along walls and ceilings.

You have disadvantage on all Strength saving throws and attack rolls while climbing.

51-55

Raven’s Cloak Mutagen

You gain advantage on Stealth checks and can cast invisibility on yourself once.

Your Armor Class is reduced by 2 while invisible, and you lose 1d4 hit points each round it’s active.

56-60

Electromagnetic Aura Mutagen

Gain an aura that shocks creatures within 10 feet, dealing 1d6 lightning damage.

You take 1d6 lightning damage at the start of each turn while this effect is active.

61-65

Blood Frenzy Mutagen

Whenever you deal melee damage, you regain hit points equal to half the damage dealt.

You take 1d6 damage at the start of each of your turns, and your AC is reduced by 2.

66-70

Sludge Form Mutagen

Gain resistance to all damage except psychic.

Your movement speed is reduced to 10 feet, and you cannot Dash or take reactions.

71-75

Mindflare Mutagen

You can cast dominate person once without using a spell slot.

After casting, you take 2d6 psychic damage and are stunned for 1 round.

76-80

Titan’s Endurance Mutagen

Gain advantage on Constitution saving throws and resistance to all damage for 1 minute.

After 1 minute, you take 4d6 damage and are poisoned for 1 minute.

81-85

Crystalline Body Mutagen

Gain +2 to AC and resistance to all magical damage.

You are vulnerable to bludgeoning damage, and your movement speed is reduced by 10 feet.

86-90

Zephyr Mutagen

Gain a flying speed equal to your walking speed.

You have disadvantage on all attack rolls while flying and take 1d6 damage each time you land.

91-95

Temporal Distortion Mutagen

Gain the ability to briefly stop time, allowing you to take an additional action on your turn.

After using the ability, you gain one level of exhaustion and cannot take reactions until your next turn.

96-99

Necrotic Surge Mutagen

When you deal damage, you can deal an additional 2d6 necrotic damage.

Each time you deal necrotic damage, you take half that damage as necrotic damage yourself.

100

Elixir of Immortality Mutagen

For 1 minute, you become immune to all damage, and your hit points cannot drop below 1.

After the effect ends, you fall unconscious, you gain 2 points of exhaustion and must succeed on a DC 15 Constitution saving throw or take 10d6 necrotic damage.

Perfected Mutagen

At 15th level, you gain access to the Perfected Mutagen Table, representing the pinnacle of your mutagenic research. You can now choose from the perfected mutagens when preparing your mutagens during a long rest. These potent formulas are balanced by more severe drawbacks but offer incredible power.

Perfected Mutagen Table

 

Mutagen	Effect	Drawback
Perfected Strength Mutagen	Gain a +5 bonus to Strength checks and saving throws, triple carrying capacity, advantage on melee attacks.	Disadvantage on Dexterity checks and saving throws, movement speed reduced by 10 feet.
Perfected Agility Mutagen	Gain a +5 bonus to Dexterity checks and saving throws, Dash/Disengage as bonus actions, advantage on ranged attacks.	Disadvantage on Strength checks and saving throws, AC decreases by 2.
Perfected Resilience Mutagen	Gain resistance to all damage types except psychic.	Disadvantage on Dexterity saving throws, movement speed reduced by 10 feet.
Perfected Celerity Mutagen	Movement speed increases by 30 feet, advantage on attack rolls during first turn, extra reaction per round.	Disadvantage on Wisdom checks and saving throws, AC decreases by 2.
Perfected Clarity Mutagen	Gain advantage on Intelligence, Wisdom, and Charisma checks and saving throws.	-3 penalty to attack rolls, disadvantage on Strength and Dexterity checks and saving throws.
Immortal Body Mutagen	Gain immunity to poison and disease, advantage on all saving throws.	Disadvantage on Dexterity checks and saving throws.
Elemental Mastery Mutagen	Gain resistance to two damage types (choose when taken).	Disadvantage on Strength and Constitution checks and saving throws.
Ultimate Reflexes Mutagen	Gain advantage on all Dexterity saving throws, AC increases by 2.	Disadvantage on Wisdom and Intelligence checks and saving throws.
Omniscient Mind Mutagen	Gain advantage on all Intelligence, Wisdom, and Charisma checks and saving throws.	Disadvantage on all Melee attack rolls.

Mutation Mastery

At 15th level, you have become a master of alchemical transformations. When you drink a mutagen or administer it to a willing creature, you can choose to ignore its drawbacks. (excluding Elixir of Immortality)

You may also, when drinking or administering an Experimental Mutagen, reroll the d100 and choose between the 2 d100 results.

Additionally, you can create a number of mutagens equal to twice your Intelligence modifier (minimum of two) when you finish a long rest.