before both disease cause reduced

Sphere of Annihilation

Magic Items Dungeon Master’s Guide

Bonus Action to cause it to move in one direction of your choice, up to a number of feet equal to 5 times your Intelligence modifier (minimum 5 feet). Any creature whose space the sphere enters must

succeed on a DC 19 Dexterity saving throw or be touched by it, taking 8d10 Force damage. A creature reduced to 0 Hit Points by this damage is obliterated, leaving its possessions behind but no other

Incarnation of Transience

Monsters Lorwyn: First Light

", "rollType":"damage", "rollAction":"Miasmic Globule", "rollDamageType":"Acid"} Acid damage, and the target’s Speed is reduced by 10 feet until the end of the incarnation’s next turn. Spectral

, transience incarnations embody the changing of seasons and the flowing of rivers. In Shadowmoor, these incarnations embody disease passing through its hosts, or the susurration of fallen leaves blowing

Harm Legacy

Spells Basic Rules (2014)

You unleash a virulent disease on a creature that you can see within range. The target must make a Constitution saving throw. On a failed save, it takes 14d6 necrotic damage, or half as much damage

on a successful save. The damage can't reduce the target's hit points below 1. If the target fails the saving throw, its hit point maximum is reduced for 1 hour by an amount equal to the necrotic

Bulezau Legacy

Monsters Mordenkainen’s Tome of Foes

hours that elapse. On a successful save, the disease ends. On a failed save, the target's hit point maximum is reduced by 4 (1d8);{"diceNotation":"1d8","rollType":"roll","rollAction":"Barbed Tail"}. The target dies if its hit point maximum is reduced to 0.PoisonCold, Fire, Lightning

+2","rollType":"damage","rollAction":"Barbed Tail","rollDamageType":"piercing"} piercing damage. If the target is a creature, it must succeed on a DC 13 Constitution saving throw against disease or

Reduced-threat Otyugh

Monsters Tales from the Yawning Portal

receiving creature to telepathically respond. Reduced Threat. This creature has -2 penalty on all ability checks and saving throws.Multiattack. The otyugh makes three attacks: one with its bite and two with

":"damage","rollAction":"Bite","rollDamageType":"piercing"} piercing damage. If the target is a creature, it must succeed on a DC 13 Constitution saving throw against disease or become poisoned until the

Death Domain (DMG)

Classes Dungeon Master’s Guide (2014)

The Death domain is concerned with the forces that cause death, as well as the negative energy that gives rise to undead creatures. Deities such as Chemosh, Myrkul, and Wee Jas are patrons of

necromancers, death knights, liches, mummy lords, and vampires. Gods of the Death domain also embody murder (Anubis, Bhaal, and Pyremius), pain (Iuz or Loviatar), disease or poison (Incabulos, Talona, or

Blue Slaad Legacy

Monsters Monster Manual (2014)

its hit point maximum is reduced by 10 (3d6);{"diceNotation":"3d6","rollType":"roll","rollAction":"Claw"} every 24 hours. If the disease reduces the target’s hit point maximum to 0, the target

damage. If the target is a humanoid, it must succeed on a DC 15 Constitution saving throw or be infected with a disease called chaos phage. While infected, the target can’t regain hit points, and

Bulezau

Monsters Mordenkainen Presents: Monsters of the Multiverse

maximum is reduced by 4 (1d8);{"diceNotation":"1d8", "rollType":"roll", "rollAction":"Barbed Tail"} until the disease ends on the target. The target dies if its hit point maximum is reduced to 0.Diseased

is a creature, it must succeed on a DC 13 Constitution saving throw against disease or become poisoned until the disease ends. While poisoned in this way, the target sports festering boils, coughs up

Tlacatecolo

Monsters Journeys through the Radiant Citadel

transforms into a Medium owl, while retaining its game statistics (other than its size). This transformation ends if the tlacatecolo is reduced to 0 hit points or if it uses its action to end it. Plague

Winds (Fiend Form Only; Recharge 5–6;{"diceNotation":"1d6","rollType":"recharge","rollAction":"Plague Winds"}). The tlacatecolo emits a chilling, disease-ridden wind in a 60-foot line that is 10 feet

Reduced-threat Aboleth

Monsters Tales from the Yawning Portal

can see the creature. Reduced Threat. This creature has -2 penalty on all ability checks and saving throws.Multiattack. The aboleth makes three tentacle attacks. Tentacle. Melee Weapon Attack: +7

","rollDamageType":"bludgeoning"} bludgeoning damage. If the target is a creature, it must succeed on a DC 12 Constitution saving throw or become diseased. The disease has no effect for 1 minute and can be removed

Death Domain

Classes Dungeon Master’s Guide (2014)

The Death domain is concerned with the forces that cause death, as well as the negative energy that gives rise to undead creatures. Deities such as Chemosh, Myrkul, and Wee Jas are patrons of

necromancers, death knights, liches, mummy lords, and vampires. Gods of the Death domain also embody murder (Anubis, Bhaal, and Pyremius), pain (Iuz or Loviatar), disease or poison (Incabulos, Talona, or

Rutterkin

Monsters Mordenkainen Presents: Monsters of the Multiverse

disease or become poisoned. At the end of each long rest, the poisoned target can repeat the saving throw, ending the effect on itself on a success. If the target is reduced to 0 hit points while

wave of fear in advance of their attacks that leaves their victims terrified and rooted in place. Creatures bitten by rutterkins are exposed to a terrible disease that infects them with the corrupting

Aboleth Legacy

Monsters Basic Rules (2014)

succeed on a DC 14 Constitution saving throw or become diseased. The disease has no effect for 1 minute and can be removed by any magic that cures disease. After 1 minute, the diseased creature’s

skin becomes translucent and slimy, the creature can’t regain hit points unless it is underwater, and the disease can be removed only by heal or another disease-curing spell of 6th level or higher

Enlarge/Reduce Legacy

Spells Basic Rules (2014)

You cause a creature or an object you can see within range to grow larger or smaller for the duration. Choose either a creature or an object that is neither worn nor carried. If the target is

damage. Reduce. The target's size is halved in all dimensions, and its weight is reduced to one-eighth of normal. This reduction decreases its size by one category--from Medium to Small, for example

Blue Slaad (control gem variant) Legacy

Monsters Monster Manual (2014)

phage. While infected, the target can't regain hit points, and its hit point maximum is reduced by 10 (3d6);{"diceNotation":"3d6","rollType":"roll","rollAction":"Claw"} every 24 hours. If the disease

":"damage","rollAction":"Claw","rollDamageType":"slashing"} slashing damage. If the target is a humanoid, it must succeed on a DC 15 Constitution saving throw or be infected with a disease called chaos

Itchi Beri

Equipment

Combat Utility Whimsy 0 1 0 Itchi berries can be harvested in clusters from under the vibrant green leaves of the Itchi plant, which are known to cause severe rashes on

exposed skin. The berries themselves are harmless and sweeten when reduced to a jam. Itchi plants are most often found on riverbanks, their leaves pointing toward the peak of Mount Arbora. Sages have speculated about this phenomenon for generations, but no conclusive evidence has laid the matter to rest.

Rutterkin Legacy

Monsters Mordenkainen’s Tome of Foes

":"damage","rollAction":"Bite","rollDamageType":"piercing"} piercing damage. If the target is a creature, it must succeed on a DC 13 Constitution saving throw against disease or become poisoned. At the end

of each long rest, the poisoned target can repeat the saving throw, ending the effect on itself on a success. If the target is reduced to 0 hit points while poisoned in this way, it dies and instantly

Dracophage Subject

Monsters Dragonlance: Shadow of the Dragon Queen

Death Throes. When the draconian is reduced to 0 hit points, it dissolves into acid that splashes on those around it. Each creature within 5 feet of the draconian must succeed on a DC 12 Dexterity

throw or be infected with a disease—a minuscule slaad egg. A Humanoid host can carry only one slaad egg at a time. Over three months, the egg moves to the chest cavity, gestates, and forms a

Oinoloth

Monsters Mordenkainen Presents: Monsters of the Multiverse

addition, the oinoloth can end one disease on the target or remove one of the following conditions from it: blinded, deafened, paralyzed, or poisoned. The target then gains 1 level of exhaustion, and

its hit point maximum is reduced by 7 (2d6);{"diceNotation":"2d6", "rollType":"roll", "rollAction":"Corrupted Healing"}. This reduction can be removed only by a wish spell or by casting greater

Oinoloth Legacy

Monsters Mordenkainen’s Tome of Foes

hit points. After every 24 hours that elapse, the poisoned creature can repeat the saving throw. On a failed save, the creature's hit point maximum is reduced by 5 (1d10);{"diceNotation":"1d10

","rollType":"roll"}. This reduction lasts until the poison ends, and the target dies if its hit point maximum is reduced to 0. The poison ends after the creature successfully saves against it three times

Doomguard Rot Blade

Monsters Planescape: Adventures in the Multiverse

, except for magic items, reduced to ash. Hit or Miss: The rot blade can cause the blade to emit a burst of entropic magic in a 10-foot-radius sphere centered on the weapon. Each creature in that area

everything it is wearing or carrying, except for magic items, reduced to ash.Rot blades are the entropic levers through which the Doomguard quickens the natural decay of the multiverse. These members wield weapons immersed in necrotic energy, which can turn their enemies to ash.Necrotic

Scissors of Shadow Snipping

Magic Items The Wild Beyond the Witchlight

As an action, you make a few snips with these iron shears and cause the shadow of a Humanoid creature you can see within 5 feet of you to detach from its source. If the creature is unwilling to give

next dawn. The shadow (variant);detached shadow is rooted to the spot where it was snipped until you use a bonus action to cause it to behave in one of the following ways, either of which is possible

Zuggtmoy Legacy

Monsters Out of the Abyss

infected by these spores for 24 hours. On a failed save, the creature is infected with a disease called the spores of Zuggtmoy and also gains a random form of madness (determined by rolling on the Madness

of Zuggtmoy table) that lasts until the creature is cured of the disease or dies. While infected in this way, the creature can’t be reinfected, and it must repeat the saving throw at the end of

Martial Arts Adept

Monsters Mordenkainen Presents: Monsters of the Multiverse

":"damage","rollAction":"Unarmed Strike","rollDamageType":"bludgeoning"} bludgeoning damage. Once per turn, the adept can cause one of the following additional effects (choose one or roll a d4

by a ranged weapon attack, the adept deflects the missile. The damage it takes from the attack is reduced by 1d10 + 3;{"diceNotation":"1d10+3","rollType":"roll","rollAction":"Deflect Missile"}. If the

Vegepygmy

Monsters Mordenkainen Presents: Monsters of the Multiverse

poison or cures disease kills the infestation. A creature reduced to 0 hit points by the mold dies. If the dead creature is a Beast, a Giant, or a Humanoid, one or more vegepygmies emerge from its body 24

alcohol, or magic that cures disease kills russet mold in a square area that is 10 feet on a side. Sunlight kills any russet mold in the light’s area.Lightning, Piercing

Shield of the Blazing Dreadnought

Magic Items Bigby Presents: Glory of the Giants

can cause the shield to flare with the cleansing fire of the god Surtur. Choose one creature you can see within 30 feet of yourself (you can choose yourself). One disease or condition of your choice

House of Cards

Magic Items The Book of Many Things

This deck of cards is decorated with geometric shapes that have a protective motif. While you’re holding the deck, you can use an action to shuffle it and cause the cards to deal themselves out

psychic damage. The shelter lasts for 24 hours, until you dismiss it as an action, or until it is reduced to 0 hit points. When the shelter’s duration ends, it transforms back into a deck of cards

Zuggtmoy

Monsters Mordenkainen Presents: Monsters of the Multiverse

, if it is reduced to 0 hit points, each creature within 10 feet of it takes poison damage equal to its number of Hit Dice. Poison; Bludgeoning, Piercing, and Slashing that is NonmagicalCold, Fire

infected with a disease called the spores of Zuggtmoy, which lasts until the creature is cured of the disease or dies. While infected in this way, the creature can’t be reinfected, and it must

Thorny Vegepygmy

Monsters Mordenkainen Presents: Monsters of the Multiverse

start of each of its turns. The creature can repeat the saving throw at the end of each of its turns, ending the effect on itself on a success. Any magic that neutralizes poison or cures disease kills

the infestation. A creature reduced to 0 hit points by the mold dies. If the dead creature is a Beast, a Giant, or a Humanoid, one or more vegepygmies emerge from its body 24 hours later: one from a

Vegepygmy Chief

Monsters Mordenkainen Presents: Monsters of the Multiverse

the end of each of its turns, ending the effect on itself on a success. Any magic that neutralizes poison or cures disease kills the infestation. A creature reduced to 0 hit points by the mold dies

, or radiant damage kill 1 square foot of russet mold per 1 damage dealt. A pound of salt, a gallon of alcohol, or magic that cures disease kills russet mold in a square area that is 10 feet on a side. Sunlight kills any russet mold in the light’s area.Lightning, Piercing

Carrion Stalker

Monsters Van Richten’s Guide to Ravenloft

infest its body. The creature can repeat the saving throw at the end of each of its turns, ending the effect on itself on a success. Any effect that cures disease or removes the poisoned condition

instantly kills the larvae in the creature, ending the effect on it. If a creature is reduced to 0 hit points by the infestation, it dies. The larvae remain in the corpse, and one survives to become a fully

Catoblepas

Monsters Mordenkainen Presents: Monsters of the Multiverse

necrotic damage. The target dies if reduced to 0 hit points by this ray.The catoblepas is as loathsome as the vile swamplands in which it lives, a conglomeration of bloated buffalo, dinosaur, warthog

disease and decay brings out similar characteristics in the creature’s swampy habitat. Such a wetland becomes gloomy, tangled, and more fetid than it was before. Beneficial qualities of the

Demilich Legacy

Monsters Monster Manual (2014)

Drain (Costs 2 Actions). Each creature within 30 feet of the demilich must make a DC 15 Constitution saving throw. On a failed save, the creature’s hit point maximum is magically reduced by 10 (3d6

);{"diceNotation":"3d6","rollType":"roll","rollAction":"Energy Drain"}. If a creature’s hit point maximum is reduced to 0 by this effect, the creature dies. A creature’s hit point maximum

Venom Troll

Monsters Mordenkainen Presents: Monsters of the Multiverse

15-foot cube. The troll takes 7 (2d6);{"diceNotation":"2d6", "rollType":"damage", "rollAction":"Venom Spray", "rollDamageType":"slashing"} slashing damage, which can’t be reduced in any way. Each

;rot trolls, spirit troll;spirit trolls, and venom trolls that follow are especially likely to arise when trolls regenerate in the presence of magical emanations, planar energy, disease, or death on a

Dybbuk

Monsters Mordenkainen Presents: Monsters of the Multiverse

", "rollAction":"Tentacle", "rollDamageType":"necrotic"} necrotic damage. If the target is a creature, its hit point maximum is also reduced by 3 (1d6);{"diceNotation":"1d6", "rollType":"roll", "rollAction

":"Tentacle"}. This reduction lasts until the target finishes a short or long rest. The target dies if its hit point maximum is reduced to 0. Possess Corpse (Recharge 6);{"diceNotation":"1d6

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